Cefdinir refrigerated

In recent years, there has been a growing concern about the environmental impact of refrigerants used in various industries. As a result, many businesses are now looking for ways t...

Cefdinir refrigerated. Doxycycline is in a class of medications called tetracycline antibiotics. Doxycycline is a versatile antibiotic that belongs to the tetracycline class of medications. It is commonly prescribed to treat a wide range of bacterial infections. In this article, we will explore the uses and differences between doxycycline mono and doxycycline hyclate, discuss their …

nausea, vomiting, stomach pain, diarrhea; vaginal itching or discharge; headache; or. rash (including diaper rash in an infant taking liquid cefdinir. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Find information on Cefdinir (Omnicef) in Davis’s Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF.Cefdinir left out of refrigerator. This seems like an interesting pharmacy controversy. We have an aux sticker that goes on the bottle that says "DO NOT REFRIGERATE" but the sticker was put on the box instead of the bottle and the parents took the bottle home and threw it straight in the fridge.Cefdinir was approved by the FDA in 1997 to treat a variety of mild to moderate infections and was initially marketed by Abbvie. 6 Because of its chemical structure, it is effective against organisms that are resistant to first-line cephalosporin therapy due to the production of beta-lactamase enzymes. 2, 3. Type. Small Molecule. Groups. Approved.Read More. Clavamox can actually be stored outside of the refrigerated and doesn't lose potency or become harmful if not refrigerated for 2 weeks or more at moderate temperatures. If the temperature in your home is above 80 degrees it will lose potency quicker, but will not cause any harm. Read More.Cefdinir USP is a white to slightly brownish-yellow solid. It is slightly soluble in dilute hydrochloric acid and sparingly soluble in 0.1 M pH 7.0 phosphate buffer. The molecular formula is C14H13N5O5S2 and the molecular weight is 395.42. Cefdinir left out of refrigerator. This seems like an interesting pharmacy controversy. We have an aux sticker that goes on the bottle that says "DO NOT REFRIGERATE" but the sticker was put on the box instead of the bottle and the parents took the bottle home and threw it straight in the fridge. They called this morning and I asked the mother ...

Are you in the market for a new refrigerator? With so many options available, choosing the right one can be overwhelming. One factor that plays a significant role in the decision-m...nausea, vomiting, stomach pain, diarrhea; vaginal itching or discharge; headache; or. rash (including diaper rash in an infant taking liquid cefdinir. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.Refrigerating Cefdinir does not significantly affect its effectiveness, but it is generally recommended to store it at room temperature. Learn about the impact of refrigerating Cefdinir, how to store it properly, and what to do if you accidentally refrigerated it.Effect of Food. The C max and AUC of cefdinir from the capsules are reduced by 16% and 10%, respectively, when given with a high-fat meal. In adults given the 250 mg/5 mL oral suspension with a high-fat meal, the C max and AUC of cefdinir are reduced by 44% and 33%, respectively. The magnitude of these reductions is not likely to be clinically …Fifty miles south of Nashville, outside the city of Columbia, where the restaurants offer Bar-B-Q and catfish, is an unlikely piece of smokestack America. There, nestled amid the p...Cefdinir is a white to slightly brownish-yellow solid. It is slightly soluble in dilute hydrochloric acid and sparingly soluble in 0.1 M pH 7.0 phosphate buffer.The empirical formula is C14H13N5O5S2 and the molecular weight is 395.42. Cefdinir has the structural formula shown below: [cefdinir-structure]Learn how to store cefdinir, an antibiotic for bacterial infections, at room temperature or in the fridge. Find out why freezing cefdinir is not recommended and how long it lasts in the fridge.

BUY Cefdinir (Cefdinir) 300 mg/1 by Teva Pharmaceuticals USA, Inc.. Get quick delivery of medicines online from GNH India at the best price. GNH India is a Global Pharmaceuticals Distributor with shipping to over 180 countries globally. ... utilizing thermal and refrigerated packaging methods. Read more . About GNH. We deliver your …Descriptions. Cefdinir is used to treat bacterial infections in many different parts of the body. It belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.Mar 28, 2024 · Keep taking Omnicef (cefdinir suspension) as you have been told by your doctor or other health care provider, even if you feel well. Take with or without food. Take with food if it causes an upset stomach . Do not take antacids that have aluminum or magnesium in them within 2 hours of Omnicef (cefdinir suspension). A literature survey revealed that few analytical methods are available for the estimation of cefdinir from bulk drugs / dosage forms[7–16] and from human plasma.[] The reported method for the estimation of cefdinir includes HPLC,[7–11] the ultraviolet (UV) spectroscopic and colorimetric method,[12–13] and the spectroflourimetric method of analysis.[]

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Precautions. Interactions. Overdose. Uses. Cefdinir is used to treat a wide variety of bacterial infections. This medication is known as a cephalosporin antibiotic. It works by stopping the...Cefdinir was not teratogenic in rats at oral doses up to 1000 mg/kg/day (70 times the human dose based on mg/kg/day, 11 times based on mg/m 2 /day) or in rabbits at oral doses up to 10 mg/kg/ day (0.7 times the human dose based on mg/kg/day, 0.23 times based on mg/m 2 /day). Maternal toxicity (decreased body weight gain) was observed in …Accidentally stored cefdinir 250 mg/5 ml susp in the refrigerator overnight and left it ar rt in the morning. will it spoil it or decrease its effect? A doctor has provided 1 answer Dr. Jan Lei Iwata answeredBest Answer. I did the same thing. I called the pharmacy and they said it would be fine - it just gets thick. Wiki User. ∙ 12y ago. Q: What happens if you refrigerate Cefdinir generic for Omnicef by mistake? I did the same thing. I called the pharmacy and they said it would be fine - it just gets thick.Customer: Hello - Today my pediatrician prescribed Cefdinir 250 mg (disp for Omnicef) for my 3 year old daughters UTI. I put the bottle in the fridge after giving it to her this morning, and then tonight I saw that it says "DO NOT REFRIGERATE" on the bottle.

Cefdinir was not teratogenic in rats at oral doses up to 1000 mg/kg/day (70 times the human dose based on mg/kg/day, 11 times based on mg/m. 2 /day) or in rabbits at oral doses up to 10 mg/kg/day (0.7 times the human dose based on mg/kg/day, 0.23 times based on mg/m. 2 /day). Maternal toxicity (decreased body weight gain) was observed in ...Uses. Cefdinir is used to treat a wide variety of bacterial infections. This medication is known as a cephalosporin antibiotic. It works by stopping the growth of bacteria.This antibiotic treats ...Cefdinir belongs to a group of medications called third generation cephalosporins. Cefdinir is a medication sold under the brand name Omnicef by Abbot ...Sometimes chilling oral meds can help with taste issues. Some meds don’t need refrigeration (I don’t know about Cefdinir) but unless it shouldn’t be refrigerated I would do that. She might just still be genuinely feeling bad from the infection if it hasn’t been 48 hours, and she might want the comfort and cuddling.Cefdinir may cause any of the following side effects: diarrhea, headache and nausea. If you develop rashes, breathlessness, swollen mouth or eyes, stop the medicine and inform your doctor quickly. These could be signs of an allergic reaction. Inform your doctor if any of these side effects do not go away or are severe, or if you experience ...Having a refrigerator that is not cooling can be a major inconvenience. Fortunately, there are some easy steps you can take to troubleshoot and fix the issue. Here is how to fix a ...Effect of Food. The C max and AUC of cefdinir from the capsules are reduced by 16% and 10%, respectively, when given with a high-fat meal. In adults given the 250 mg/5 mL oral suspension with a high-fat meal, the C max and AUC of cefdinir are reduced by 44% and 33%, respectively. The magnitude of these reductions is not likely to be clinically …Cefdinir USP is a white to slightly brownish-yellow solid. It is slightly soluble in dilute hydrochloric acid and sparingly soluble in 0.1 M pH 7.0 phosphate buffer. The molecular formula is C14H13N5O5S2 and the molecular weight is 395.42. conducted without regard to food intake. Therefore, cefdinir may be taken without regard to food. Cefdinir SuspensionCefdinir plasma concentrations and pharmacokinetic parameter values : following administration of single 7 and 14 mg/kg oral doses of cefdinir to pediatric subjects (age 6 months-12 years) are presented in the following table: Amoxicillin is a broad-spectrum antibiotic used to treat various bacterial infections. It is a semi-synthetic penicillin that works by stopping the growth and multiplication of bacteria. Amoxicillin is available in different forms such as capsules, tablets, and oral suspension.Keyword Research: People who searched cefdinir put in fridge also searched

Apr 28, 2022 · Best Answer. I did the same thing. I called the pharmacy and they said it would be fine - it just gets thick. Wiki User. ∙ 12y ago. Q: What happens if you refrigerate Cefdinir generic for Omnicef by mistake? I did the same thing. I called the pharmacy and they said it would be fine - it just gets thick.

By H. influenzae, S. pneumoniae (penicillin-susceptible strains only) and M. catarrhalis. Uncomplicated skin and skin-structure infections caused by S. aureus (MSSA) and S. pyogenes. There's more to see -- the rest of this topic is available only to subscribers. Cefdinir answers are found in the Johns Hopkins ABX Guide powered by Unbound …It never happened to us but it was something the doctor and pharmacist said could happen as a normal side effect. Another option for you would be to call the pharmacy where you filled the prescription and ask to speak to the pharmacist about it. They are usually able to help with routine questions about medications. 2.May 1, 2024 · Omnicef; Descriptions. Cefdinir is used to treat bacterial infections in many different parts of the body. It belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections. Cefdinir has the structural formula shown below: Cefdinir capsules, USP contain 300 mg cefdinir and the following inactive ingredients: carboxymethylcellulose calcium, polyoxyl 40 stearate, colloidal silicone dioxide and magnesium stearate. The capsule shells contain FD&C Blue #2; gelatin, titanium dioxide, gelatin and water.Cefdinir is a third-generation oral cephalosporin antibiotic. Nomenclature, formulae, elemental analysis, and appearance of the drug are mentioned. The uses and applications and the several methods described for its preparation of the drug are outlined. The profile contains the physical characteristics including: pKa value, solubility, X-ray ...Bronchitis, acute exacerbation: Oral: Adolescents: 300 mg every 12 hours for 5 to 10 days or 600 mg every 24 hours for 10 days. Otitis media, acute: Infants ≥6 months and Children: Oral: 14 mg/kg/day in divided doses every 12 to 24 hours for 5 to 10 days; maximum daily dose: 600 mg/ day.Cefdinir for Oral Suspension, USP 125 mg/5 mL is a off-white to yellowish — white colored granular powder, on constitution with water, forming an off-white to yellowish-white colored suspension with strawberry and cream flavors. 60 mL Bottle 100 mL Bottle. NDC 16714-392-01 NDC 16714-392-02.Do not throw cefdinir in the trash or flush it down the toilet. The best way to dispose of expired or unneeded cefdinir is through your local waste disposal company or a drug take-back program. Learn more about proper medication disposal. NOTE: This medication guide is a summary and may not contain all possible drug information on …Cefdinir may cause any of the following side effects: diarrhea, headache and nausea. If you develop rashes, breathlessness, swollen mouth or eyes, stop the medicine and inform your doctor quickly. These could be signs of an allergic reaction. Inform your doctor if any of these side effects do not go away or are severe, or if you experience ...Metabolism and Excretion: Cefdinir is not appreciably metabolized. Activity is primarily due to parent drug. Cefdinir is eliminated principally via renal excretion with a mean plasma elimination half-life (t 1/2) of 1.7 (±0.6) hours.In healthy subjects with normal renal function, renal clearance is 2.0 (±1.0) mL/min/kg, and apparent oral clearance is …

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Side Effects. Diarrhea, nausea, vomiting, headache, or diaper rash in young children may occur. If any of these effects last or get worse, notify your doctor or pharmacist promptly. This ...By H. influenzae, S. pneumoniae (penicillin-susceptible strains only) and M. catarrhalis. Uncomplicated skin and skin-structure infections caused by S. aureus (MSSA) and S. pyogenes. There's more to see -- the rest of this topic is available only to subscribers. Cefdinir answers are found in the Johns Hopkins ABX Guide powered by Unbound Medicine.Check your drip pan for standing water before you're dealing with leaks and mold. Keeping your refrigerator clean is easy when there are obvious spills or food bits or expired item...Find information on Cefdinir (Omnicef) in Davis’s Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF.Hence, the line of management would be- - Discontinue the Cefdinir (as already done) - This will subside the reaction within a week. I haven’t heard anything about keeping the bocep refrigerated. I peeled back the label on the vial and read that it should be kept refridgerated between 36 and 46 degrees.Keep taking Omnicef (cefdinir suspension) as you have been told by your doctor or other health care provider, even if you feel well. Take with or without food. Take with food if it causes an upset stomach . Do not take antacids that have aluminum or magnesium in them within 2 hours of Omnicef (cefdinir suspension).Keyword Research: People who searched cefdinir suspension refrigerate or not also searchedCefdinir has not been studied for use during labor and delivery. Nursing Mothers: Following administration of single 600 mg doses, cefdinir was not detected in human breast milk. Pediatric Use: Safety and efficacy in neonates and infants less than 6 months of age have not been established. Use of cefdinir for the treatment of acute maxillary ...Medications Stored in the Refrigerator. Get concise advice on drug therapy, plus unlimited access to CE. Pharmacist's Letter includes: 12 issues every year, ... ….

PRECAUTIONS: Before taking cefdinir, tell your doctor or pharmacist if you are allergic to it; or to penicillins or other cephalosporin antibiotics (e.g., cephalexin); or if you have any other allergies.This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell …Omnicef, also known as cefdinir, is a broad-spectrum antibiotic used to treat various types of bacterial infections. It does this by inhibiting the synthesis of peptidoglycan, an essential component for bacterial cell walls. By doing so, Omnicef weakens the bacteria's structural integrity and eventually causes them to burst open and die.If you have a used refrigerator that you no longer need, selling it can be a great way to make some extra cash. However, finding the right buyer and getting a fair price can someti...The dose is usually 7 milligrams (mg) per kilogram (kg) of body weight every twelve hours or 14 milligrams (mg) per kilogram (kg) of body weight per day, taken for 5 to 10 days. However, the dose is usually not more than 600 mg per day. Infants up to 6 months of age—Use and dose must be determined by your doctor.May 29, 2022 · Amoxicillin capsules and tablets have an expiry of around 2 years and, provided they are stored as recommended and in the original packaging, there will be a small lee way of safety if used beyond expiry. Amoxicillin suspension is different and has a very short shelf life of about 7-10 days once it is prepared. Effect of Food. The C max and AUC of cefdinir from the capsules are reduced by 16% and 10%, respectively, when given with a high-fat meal. In adults given the 250 mg/5 mL oral suspension with a high-fat meal, the C max and AUC of cefdinir are reduced by 44% and 33%, respectively. The magnitude of these reductions is not likely …You can leave the follistim at the room temperature but you have to use it within 90 days. if you leave it in the refrigerator, it could last for 6 months. Mostly we will use it all so either refrigerator or room temperature is fine. Today is my CD6. I did injected follistim on CD3 and CD5.Feb 14, 2024 · Cefdinir for oral suspension, USP after reconstitution, contains 125 mg cefdinir USP per 5 mL or 250 mg cefdinir USP per 5 mL and the following inactive ingredients: sucrose, sodium benzoate, colloidal silicone dioxide, xanthan gum, guar gum, citric acid (anhydrous), sodium citrate (dihydrate), strawberry flavour, fresh cream flavour and ... Results. The results showed that 347 (86.8 %) of mothers told that they read instructions, 311 (77.8 %) could understand manufacturers’ instructions, and 176 (44.0 %) of mothers asked pharmacists for advice when instructions were not well understood. Cefdinir refrigerated, Jun 27, 2017 · nausea, vomiting, stomach pain, diarrhea; vaginal itching or discharge; headache; or. rash (including diaper rash in an infant taking liquid cefdinir. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. , Cefdinir مضاد للجراثيم سلبية الغرام (بالإنجليزية: gram negative)، ما عدا الزائفة الزنجارية (بالإنجليزية: Pseudomonas Aeruginosa)، وله أثر على بعض الجراثيم إيجابية الغرام (بالإنجليزية: gram positive)., Effect of Food. The C max and AUC of cefdinir from the capsules are reduced by 16% and 10%, respectively, when given with a high-fat meal. In adults given the 250 mg/5 mL oral suspension with a high-fat meal, the C max and AUC of cefdinir are reduced by 44% and 33%, respectively. The magnitude of these reductions is not likely to be clinically …, Nov 12, 2006 ... Ds is on his next lot of AB's, I got them on Friday and put them in the fridge because that's what I had to do with a different sort he had ..., Uses. Cefdinir is used to treat a wide variety of bacterial infections. This medication is known as a cephalosporin antibiotic. It works by stopping the growth of bacteria.This antibiotic treats ..., Identification Summary. Cefdinir is a third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections.. Generic Name Cefdinir DrugBank Accession Number DB00535 Background. Cefdinir, also known as Omnicef, is a semi-synthetic, broad-spectrum antibiotic belonging to the third generation of the …, Clavamox can actually be stored outside of the refrigerated and doesn't lose potency or become harmful if not refrigerated for 2 weeks or more at moderate temperatures. If the temperature in your home is above 80 degrees it will lose potency quicker, but will not cause any harm. Read More., Give this drug with or without food. Give with food if it causes an upset stomach. Use as you have been told, even if your child’s signs get better. Do not take antacids that have aluminum or magnesium in them within 2 hours of this drug. Do not give iron products within 2 hours before or 2 hours after giving this drug., Effect of Food. The C max and AUC of cefdinir from the capsules are reduced by 16% and 10%, respectively, when given with a high-fat meal. In adults given the 250 mg/5 mL oral suspension with a high-fat meal, the C max and AUC of cefdinir are reduced by 44% and 33%, respectively. The magnitude of these reductions is not likely …, Yes, Cefdinir does expire. The stability and potency of Cefdinir, once it is past the expiration date, depends on the type of dosage form it has been formulated into. A solid oral dosage form of Cefdinir can remain potent even after the expiration date. It can take up to years for the drug to lose its potency if it is stored in ideal conditions., conducted without regard to food intake. Therefore, cefdinir may be taken without regard to food. Cefdinir SuspensionCefdinir plasma concentrations and pharmacokinetic parameter values : following administration of single 7 and 14 mg/kg oral doses of cefdinir to pediatric subjects (age 6 months-12 years) are presented in the following table:, The intent of this project was to determine the completeness of information on the maximum duration at which refrigerated medications can tolerate room temperature (RT) excursions while maintaining stability and potency. RT was defined as 20 to 25 degrees Celsius (68-77 degrees Fahrenheit) based on the United States …, Yes, Cefdinir does expire. The stability and potency of Cefdinir, once it is past the expiration date, depends on the type of dosage form it has been formulated into. A solid oral dosage form of Cefdinir can remain potent even after the expiration date. It can take up to years for the drug to lose its potency if it is stored in ideal conditions., Are you tired of that old refrigerator taking up space in your home? Do you want to get rid of it but don’t want to pay for removal services? Look no further. In this article, we w..., Cefdinir left out of refrigerator. This seems like an interesting pharmacy controversy. We have an aux sticker that goes on the bottle that says "DO NOT REFRIGERATE" but the sticker was put on the box instead of the bottle and the parents took the bottle home and threw it straight in the fridge. They called this morning and I asked the mother ..., Cefdinir (Omnicef®) Footnote 1 []is an oral expanded-spectrum, third-generation cephalosporin with improved stability against many common β-lactamases, a distinct advantage over first and second generation cephalosporins in the treatment of β-lactamase-producing strains of Haemophilus influenzae and Moraxella …, Uses. Cefdinir is used to treat a wide variety of bacterial infections. This medication is known as a cephalosporin antibiotic. It works by stopping the growth of bacteria.This antibiotic treats ..., You can leave the follistim at the room temperature but you have to use it within 90 days. if you leave it in the refrigerator, it could last for 6 months. Mostly we will use it all so either refrigerator or room temperature is fine. Today is my CD6. I did injected follistim on CD3 and CD5., Apr 26, 2012 · Answers. This is the storage information from the monograph ... so I guess you could put it in a cool place, not necessarily in the fridge. Store the capsules and unsuspended powder at 25°C (77°F); excursions permitted to 15°-30°C (59°-86°F). Once reconstituted, the oral suspension can be stored at controlled room temperature for 10 days. , Serious side effects from antibiotics are more rare, and can include: C. diff infection: a form of diarrhea caused when the bacteria C. difficile overgrows in the gut. Allergic reactions: which may cause difficulty breathing, hives, or swelling of the face and hands. Keep in mind that this isn’t a complete list., Cefdinir is a white to slightly brownish-yellow solid. It is slightly soluble in dilute hydrochloric acid and sparingly soluble in 0.1 M pH 7.0 phosphate buffer. The molecular formula is C 14 H 13 N 5 O 5 S 2 and the molecular weight is 395.42. Cefdinir has the structural formula shown below:, 125 mg/5 mL & 250 mg/5 mL. Rx only. To reduce the development of drug-resistant bacteria and maintain the effectiveness of cefdinir for oral suspension and other antibacterial drugs, cefdinir for oral suspension should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria., Cefdinir can affect the results of certain medical tests. Tell any doctor who treats you that you are using cefdinir. Store at room temperature away from moisture and heat., Cefdinir for oral suspension, USP after reconstitution, contains 125 mg cefdinir USP per 5 mL or 250 mg cefdinir USP per 5 mL and the following inactive ingredients: sucrose, sodium benzoate, colloidal silicone dioxide, xanthan gum, guar gum, citric acid (anhydrous), sodium citrate (dihydrate), strawberry flavour, fresh cream flavour and ..., Store cefdinir suspension at room temperature (68-77°F [20-25°C]), away from moisture and heat and shake well before each administration. Use a measuring spoon to measure the correct dose. Discard any unused portion after 10 days., Read More. you can find it in the refrigerated section at Fred Meyer, Super Supplements, etc.) Get quality Flaxoil that needs to be refrigerated and that is "cold pressed" so you get all the benefits. Flaxoil is great for your eyes, hair, skin, etc. and you should notice the difference with your dry eye., Feb 15, 2022 ... Most liquid antibiotics are refrigerated to maintain their effectiveness and taste. However, it is not necessary to keep all antibiotics in ..., Identification Summary. Cefdinir is a third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections.. Generic Name Cefdinir DrugBank Accession Number DB00535 Background. Cefdinir, also known as Omnicef, is a semi-synthetic, broad-spectrum antibiotic belonging to the third generation of the …, Sep 23, 2014 · Cefdinir capsules USP contain the active ingredient cefdinir, an extended-spectrum, semisynthetic cephalosporin, for oral administration. Chemically, cefdinir is ... Pharmacokinetics and Drug Metabolism - Absorption - Oral bioavailability - Maximal plasma cefdinir concentrations occur 2 to 4 hours postdose following capsule administration. , Fifty miles south of Nashville, outside the city of Columbia, where the restaurants offer Bar-B-Q and catfish, is an unlikely piece of smokestack America. There, nestled amid the p..., Active drugs used in medications are temperature-sensitive. When stored in hot or cold places, they can become unstable and even degrade, posing a risk of negative side effects and decreasing their effectiveness. Drug companies are required to strictly control temperatures during manufacturing. And most medications must be stored at a ..., Jan 1, 2018 ... Once reconstituted, these oral suspensions should be refrigerated to preserve their potency and deliver optimal benefit to the patient., Precautions. Interactions. Overdose. Uses. Cefdinir is used to treat a wide variety of bacterial infections. This medication is known as a cephalosporin antibiotic. It works by stopping the...